Ralfinamide mesylate( FCE-26742A (mesylate) )

Catalog No. M20790 CAS No. 202825-45-4

Ralfinamide mesylate is an orally available Na+ channel blocker.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Ralfinamide mesylate
Note

Research use only, not for human use.
Brief Description

Ralfinamide mesylate is an orally available Na+ channel blocker.
Description

Ralfinamide mesylate is an orally available Na+ channel blocker.
In Vitro

——
In Vivo

Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain. Animal Model:81 adult male Sprague–Dawley male rats (260–460 g) Dosage:80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative)Administration:Oral gavage; twice daily; until postoperative day 42 Result:Suppressed neuropathic pain.
Synonyms

FCE-26742A (mesylate)
Pathway

Membrane Transporter/Ion Channel
Target

Sodium Channel
Recptor

Sodium Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

202825-45-4
Formula Weight

398.45
Molecular Formula

C18H23FN2O5S?
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(NCc1ccc(OCc2ccccc2F)cc1)C(N)=O.CS(=O)(=O)O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Liang X Yu G Su R . Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain[J]. European journal of pharmacology 2018 823:27-34.

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