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Ralfinamide mesylate

CAS No. 202825-45-4

Ralfinamide mesylate( FCE-26742A (mesylate) )

Catalog No. M20790 CAS No. 202825-45-4

Ralfinamide mesylate is an orally available Na+ channel blocker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ralfinamide mesylate
  • Note
    Research use only, not for human use.
  • Brief Description
    Ralfinamide mesylate is an orally available Na+ channel blocker.
  • Description
    Ralfinamide mesylate is an orally available Na+ channel blocker.
  • In Vitro
    ——
  • In Vivo
    Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain. Animal Model:81 adult male Sprague–Dawley male rats (260–460 g) Dosage:80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative)Administration:Oral gavage; twice daily; until postoperative day 42 Result:Suppressed neuropathic pain.
  • Synonyms
    FCE-26742A (mesylate)
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Sodium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    202825-45-4
  • Formula Weight
    398.45
  • Molecular Formula
    C18H23FN2O5S?
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(NCc1ccc(OCc2ccccc2F)cc1)C(N)=O.CS(=O)(=O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liang X Yu G Su R . Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain[J]. European journal of pharmacology 2018 823:27-34.
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